Dihydrouracil

Names

[ CAS No. ]:
504-07-4

[ Name ]:
Dihydrouracil

[Synonym ]:
dihydropyrimidine-2,4(1H,3H)-dione
T6MVMVTJ
EINECS 207-982-1
Dihydrouracil
2,4(1H,3H)-Pyrimidinedione, dihydro-
5,6-DIHYDROURACIL
Dihydro-2,4(1H,3H)-pyrimidinedione
1,3-diazinane-2,4-dione
MFCD00006029

Biological Activity

[Description]:

5,6-Dihydrouracil is an intermediate breakdown product of uracil.

[Related Catalog]:

Research Areas >> Others

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
337.0±25.0 °C at 760 mmHg

[ Melting Point ]:
279-281 °C(lit.)

[ Molecular Formula ]:
C₄H₆N₂O₂

[ Molecular Weight ]:
114.103

[ Flash Point ]:
208.5±12.4 °C

[ Exact Mass ]:
114.042931

[ PSA ]:
58.20000

[ LogP ]:
-1.83

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.649

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

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Kidney Int. 79(11) , 1244-53, (2011)

Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used...

Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands.

Nucleic Acids Res. 42(10) , 6300-13, (2014)

The human thymine-DNA glycosylase (TDG) initiates the base excision repair (BER) pathway to remove spontaneous and induced DNA base damage. It was first biochemically characterized for its ability to ...