Boc-GABA-OH

Names

[ Name ]:
Boc-GABA-OH

[Synonym ]:
4-[(1,1-dimethylethoxycarbonyl)amino]butanoic acid
4-Amino-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid
N-Boc-g-aminobutyric Acid
Glutamic acid, 1-(1,1-dimethylethyl) ester
Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-
Boc-GABA-OH
MFCD00037313
4-[(tert-butoxycarbonyl)amino]butanoic acid
4-(tert-butyloxycarbonylamino)butyric acid
4-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid
4-[(tert-butoxy)carbonylamino]butanoic acid
butanoic acid, 4-[[(1E)-(1,1-dimethylethoxy)hydroxymethylene]amino]-
4-(Boc-amino)butyric acid
Boc-GABA
N-Boc-gamma-aminobutyric acid
N-(tert-butyloxycarbonyl)-4-aminobutyric acid
4-(tert-Butoxycarbonylamino)butyric acid
N-Boc-γ-aminobutyric acid

Biological Activity

[Description]:

Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether

[References]

[1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
78-82 ºC

[ Melting Point ]:
55-59 °C

[ Molecular Formula ]:
C₉H₁₇NO₄

[ Molecular Weight ]:
203.236

[ Flash Point ]:
113 ºC

[ Exact Mass ]:
203.115753

[ PSA ]:
75.63000

[ LogP ]:
0.77

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.476

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
44-36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Related Compounds

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