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Butanediamide

Names

[ CAS No. ]:
110-14-5

[ Name ]:
Butanediamide

[Synonym ]:
butanediamide
Succinamide
MFCD00008042
EINECS 203-739-9

Chemical & Physical Properties

[ Density]:
1.207 g/cm3

[ Boiling Point ]:
494ºC at 760 mmHg

[ Melting Point ]:
260-265 °C (dec.)(lit.)

[ Molecular Formula ]:
C4H8N2O2

[ Molecular Weight ]:
116.11900

[ Flash Point ]:
252.6ºC

[ Exact Mass ]:
116.05900

[ PSA ]:
86.18000

[ LogP ]:
0.13780

[ Vapour Pressure ]:
6.7E-10mmHg at 25°C

[ Index of Refraction ]:
1.488

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R43

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme.

Bioorg. Med. Chem. 17 , 5414-9, (2009)

Fumarate, a four-carbon trans dicarboxylic acid, is the allosteric activator of the human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME). In this paper, we discuss the effects of the str...

Synthesis of novel melanocortin 4 receptor agonists and antagonists containing a succinamide core.

Bioorg. Med. Chem. Lett. 14 , 377, (2004)

A novel series of piperazines appended to a succinamide backbone were synthesized and found to have a high affinity for the melanocortin-4 receptor (IC(50)s ranging from <0.1 to 200 nM). Both agonists...

A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model.

Biochemistry 43(30) , 9866-76, (2004)

Sodium channel blockers are used clinically to treat a number of neuropathic pain conditions, but more potent and selective agents should improve on the therapeutic index of currently used drugs. In a...


More Articles


Related Compounds