Curcumin D6

更新时间：2024-01-20 17:14:09

Curcumin D6结构式	常用名	Curcumin D6	英文名	Curcumin D6
	CAS号	1246833-26-0	分子量	374.41700
	密度	N/A	沸点	N/A
	分子式	C₂₁H₁₄D₆O₆	熔点	N/A
	MSDS	N/A	闪点	N/A

Curcumin D6用途

Curcumin D6 (Diferuloylmethane D6) 是Curcumin (Turmeric yellow) 的氘代标记物。Curcumin (Turmeric yellow) 是一种天然酚类化合物,具有抗炎,抗氧化,抗增殖和抗血管生成等多种活性。 Curcumin是p300组蛋白乙酰转移酶 (HATs) 抑制剂,也显示对 NF-κB 和MAPKs 的抑制作用。

中文名	姜黄素-d6
英文名	(1E,6E)-1,7-bis[4-hydroxy-3-(trideuteriomethoxy)phenyl]hepta-1,6-diene-3,5-dione
英文别名	更多

描述	Curcumin D6 (Diferuloylmethane D6) 是Curcumin (Turmeric yellow) 的氘代标记物。Curcumin (Turmeric yellow) 是一种天然酚类化合物,具有抗炎,抗氧化,抗增殖和抗血管生成等多种活性。 Curcumin是p300组蛋白乙酰转移酶 (HATs) 抑制剂,也显示对 NF-κB 和MAPKs 的抑制作用。
相关类别	信号通路 >> 抗感染 >> 流感病毒信号通路 >> NF-κB信号通路 >> KEAP1-Nrf2 研究领域 >> 感染信号通路 >> 细胞凋亡 >> Ferroptosis 信号通路 >> 自噬 >> 自噬研究领域 >> 炎症/免疫信号通路 >> 自噬 >> 自噬研究领域 >> 代谢疾病信号通路 >> 表观遗传学 >> 组蛋白乙酰转移酶信号通路 >> 表观遗传学 >> 表观遗传读者域
参考文献	[1]. Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004. [2]. Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53. [3]. Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4. [4]. Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4. [5]. Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303.

描述

相关类别

信号通路 >> 抗感染 >> 流感病毒

信号通路 >> NF-κB信号通路 >> KEAP1-Nrf2

研究领域 >> 感染

信号通路 >> 细胞凋亡 >> Ferroptosis

信号通路 >> 自噬 >> 自噬

研究领域 >> 炎症/免疫

信号通路 >> 自噬 >> 自噬

研究领域 >> 代谢疾病

信号通路 >> 表观遗传学 >> 组蛋白乙酰转移酶

信号通路 >> 表观遗传学 >> 表观遗传读者域

参考文献

[1]. Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004.

[2]. Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53.

[3]. Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4.

[4]. Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4.

[5]. Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303.

分子式	C₂₁H₁₄D₆O₆
分子量	374.41700
精确质量	374.16400
PSA	93.06000
LogP	3.36990
储存条件	2-8°C，干燥，密封

危害码 (欧洲)	Xi

Halad-d6

Haidr-d6

Diferuloylmethane-d6

Curcumine-d6

Curcuma-d6

Ukon-d6

Haldar-d6

Curcumin-d6

C Yellow 15-d6

Curcumin D6

Curcumin D6用途

Curcumin D6名称

Curcumin D6生物活性

Curcumin D6物理化学性质

Curcumin D6安全信息

Curcumin D6英文别名