TCS 3035

Modify Date: 2025-08-26 05:11:05

TCS 3035 Structure
TCS 3035 structure
Common Name TCS 3035
CAS Number 871085-49-3 Molecular Weight 279.27
Density N/A Boiling Point N/A
Molecular Formula C12H9NO5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TCS 3035


GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].

 Names

Name [4-(2,4-dioxothiazolidin-5-ylidenemethyl)phenoxy]acetic acid

 TCS 3035 Biological Activity

Description GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].
Related Catalog
Target

GPR35[1]

References

[1]. Jenkins L, et al. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. Br J Pharmacol. 2011 Feb;162(3):733-48.

 Chemical & Physical Properties

Molecular Formula C12H9NO5S
Molecular Weight 279.27
Exact Mass 279.02000
PSA 118.00000
LogP 1.80270
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