TCS 3035

Modify Date: 2023-01-16 10:35:00

TCS 3035 structure	Common Name	TCS 3035
	CAS Number	871085-49-3	Molecular Weight	279.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₉NO₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TCS 3035

GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].

Name	[4-(2,4-dioxothiazolidin-5-ylidenemethyl)phenoxy]acetic acid

Description	GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	GPR35[1]
References	[1]. Jenkins L, et al. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. Br J Pharmacol. 2011 Feb;162(3):733-48.

Molecular Formula	C₁₂H₉NO₅S
Molecular Weight	279.27
Exact Mass	279.02000
PSA	118.00000
LogP	1.80270