TCS JNK 6o
Modify Date: 2024-01-13 21:49:43
TCS JNK 6o structure
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Common Name | TCS JNK 6o | ||
|---|---|---|---|---|
| CAS Number | 894804-07-0 | Molecular Weight | 356.38 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 658.6±55.0 °C at 760 mmHg | |
| Molecular Formula | C18H20N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 352.1±31.5 °C | |
Use of TCS JNK 6oJNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with ki values of 2 nM, 4 nM, 52 nM, respectively[1]. |
| Name | N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide |
|---|---|
| Synonym | More Synonyms |
| Description | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with ki values of 2 nM, 4 nM, 52 nM, respectively[1]. |
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| Related Catalog | |
| Target |
JNK1:2 nM (Ki) JNK2:4 nM (Ki) JNK3:52 nM (Ki) |
| In Vitro | JNK Inhibitor VIII (TCS JNK 6o) shows over 1000- fold selective for JNK-1 and -2 over other MAP kinases including ERK2, p38α, and p38δ[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 658.6±55.0 °C at 760 mmHg |
| Molecular Formula | C18H20N4O4 |
| Molecular Weight | 356.38 |
| Flash Point | 352.1±31.5 °C |
| Exact Mass | 356.148468 |
| PSA | 122.72000 |
| LogP | 4.86 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.599 |
| Storage condition | 2-8℃ |
| IN1283 |
| benzeneacetamide, N-(4-amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxy- |
| aminopyridine deriv. 2 |
| HMS3229K06 |
| JNK Inhibitor VIII |
| Kinome_3020 |
| N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2-(2,5-dimethoxyphenyl)acetamide |