TCS 1102
Modify Date: 2024-01-06 08:23:36
TCS 1102 structure
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Common Name | TCS 1102 | ||
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| CAS Number | 916141-36-1 | Molecular Weight | 470.58600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H26N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TCS 1102TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively).IC50 value: 0.2 nM (Ki, OX2 receptor); 3 nM (Ki, OX1 receptor) [1]Target: OX2 and OX1 receptorTCS-1102 (10 and 20 mg/kg, i.p.) were found to decrease fear and anxiety in rats 14 days after exposure to footshock.Furthermore, TCS-1102 (10 mg/kg, i.p.) was found to have anxiolytic effects that were specific for HR when tested in the elevated T-maze. [2] |
| Name | N-2-Biphenylyl-1-{[(1-methyl-1H-benzimidazol-2-yl)sulfanyl]acetyl }-L-prolinamide |
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| Synonym | More Synonyms |
| Description | TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively).IC50 value: 0.2 nM (Ki, OX2 receptor); 3 nM (Ki, OX1 receptor) [1]Target: OX2 and OX1 receptorTCS-1102 (10 and 20 mg/kg, i.p.) were found to decrease fear and anxiety in rats 14 days after exposure to footshock.Furthermore, TCS-1102 (10 mg/kg, i.p.) was found to have anxiolytic effects that were specific for HR when tested in the elevated T-maze. [2] |
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| Related Catalog | |
| References |
| Molecular Formula | C27H26N4O2S |
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| Molecular Weight | 470.58600 |
| Exact Mass | 470.17800 |
| PSA | 96.02000 |
| LogP | 5.54950 |
| TCS 1102 |