Nociceptin(1-7)(Orphanin FQ(1-7))
Modify Date: 2024-01-10 08:33:34
Nociceptin(1-7)(Orphanin FQ(1-7)) structure
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Common Name | Nociceptin(1-7)(Orphanin FQ(1-7)) | ||
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| CAS Number | 178249-42-8 | Molecular Weight | 655.69900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H41N7O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Nociceptin(1-7)(Orphanin FQ(1-7))Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo[1]. |
| Name | (2S)-2-[[2-[[(2S,3R)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]propanoic acid |
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| Synonym | More Synonyms |
| Description | Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo[1]. |
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| Related Catalog | |
| In Vivo | Nociceptin (1-7) (intrathecal injection; 150–1200 nmol; single dose) has no significant effect in the nociceptive thermal threshold (hyperalgesia). However, when nociceptin (1–7) is injected simultaneously with nociceptin (3.0 fmol), nociceptin-induced hyperalgesia is significantly reduced[1]. Animal Model: Mice[1] Dosage: 150–1200 nmol Administration: Intrathecal injection; single dose Result: Co-treatment with nociceptin could reduce hyperalgesia. |
| References |
| Molecular Formula | C31H41N7O9 |
|---|---|
| Molecular Weight | 655.69900 |
| Exact Mass | 655.29700 |
| PSA | 279.09000 |
| LogP | 2.82950 |
| TCS JNK 6o |
| L-Alanine,L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl |
- DC Chemicals Limited
- China
- Product Name: Nociceptin(1-7)
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Nociceptin (1-7)
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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