Fmoc-N-amido-PEG12-acid

Modify Date: 2024-01-13 19:47:37

Fmoc-N-amido-PEG12-acid Structure
Fmoc-N-amido-PEG12-acid structure
Common Name Fmoc-N-amido-PEG12-acid
CAS Number 850312-72-0 Molecular Weight 355.384
Density 1.3±0.1 g/cm3 Boiling Point 589.9±40.0 °C at 760 mmHg
Molecular Formula (C2H4O)n.C20H21NO5 Melting Point N/A
MSDS USA Flash Point 310.6±27.3 °C

 Use of Fmoc-N-amido-PEG12-acid


Fmoc-N-amido-PEG12-acid is a PEG derivative containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

 Names

Name O-[2-(Fmoc-amino)-ethyl]-O'-(2-carboxyethyl)polyethylene glycol 3000
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 589.9±40.0 °C at 760 mmHg
Molecular Formula (C2H4O)n.C20H21NO5
Molecular Weight 355.384
Flash Point 310.6±27.3 °C
Exact Mass 355.141968
LogP 3.37
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.589
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

MFCD16294357
Propanoic acid, 3-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]-
3-(2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)propanoic acid
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