Fmoc-N-PEG20-acid

Modify Date: 2023-01-20 10:37:24

Fmoc-N-PEG20-acid Structure
Fmoc-N-PEG20-acid structure
Common Name Fmoc-N-PEG20-acid
CAS Number 1952360-93-8 Molecular Weight 1192.383
Density 1.2±0.1 g/cm3 Boiling Point 1033.9±65.0 °C at 760 mmHg
Molecular Formula C58H97NO24 Melting Point N/A
MSDS N/A Flash Point 579.1±34.3 °C

 Use of Fmoc-N-PEG20-acid


Fmoc-N-amido-PEG20-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-N-amido-PEG20-acid
Synonym More Synonyms

 Fmoc-N-PEG20-acid Biological Activity

Description Fmoc-N-amido-PEG20-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 1033.9±65.0 °C at 760 mmHg
Molecular Formula C58H97NO24
Molecular Weight 1192.383
Flash Point 579.1±34.3 °C
Exact Mass 1191.640015
LogP -3.43
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.502

 Synonyms

MFCD21363316
2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-Heneicosaoxa-4-azaheptahexacontan-67-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-henicosaoxa-4-azaheptahexacontan-67-oic acid