850312-72-0
850312-72-0 structure
- Name: Fmoc-N-amido-PEG12-acid
- Chemical Name: O-[2-(Fmoc-amino)-ethyl]-O'-(2-carboxyethyl)polyethylene glycol 3000
- CAS Number: 850312-72-0
- Molecular Formula: (C2H4O)n.C20H21NO5
- Molecular Weight: 355.384
- Create Date: 2018-12-16 15:44:24
- Modify Date: 2025-08-31 17:31:10
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Fmoc-N-amido-PEG12-acid is a PEG derivative containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
| Name | O-[2-(Fmoc-amino)-ethyl]-O'-(2-carboxyethyl)polyethylene glycol 3000 |
|---|---|
| Synonyms |
MFCD16294357
Propanoic acid, 3-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]- 3-(2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)propanoic acid |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 589.9±40.0 °C at 760 mmHg |
| Molecular Formula | (C2H4O)n.C20H21NO5 |
| Molecular Weight | 355.384 |
| Flash Point | 310.6±27.3 °C |
| Exact Mass | 355.141968 |
| LogP | 3.37 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.589 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |