Top Suppliers:I want be here

2378428-27-2

2378428-27-2 structure
2378428-27-2 structure
  • Name: Mal-amido-PEG12-acid
  • Chemical Name: Mal-amido-PEG12-acid
  • CAS Number: 2378428-27-2
  • Molecular Formula: C34H60N2O17
  • Molecular Weight: 768.84
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:34:47
  • Modify Date: 2024-01-03 20:29:36
  • Mal-amido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-amido-PEG12-acid
Description Mal-amido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C34H60N2O17
Molecular Weight 768.84