Mal-amido-PEG12-acid

Modify Date: 2024-01-03 20:29:36

Mal-amido-PEG12-acid Structure
Mal-amido-PEG12-acid structure
Common Name Mal-amido-PEG12-acid
CAS Number 2378428-27-2 Molecular Weight 768.84
Density N/A Boiling Point N/A
Molecular Formula C34H60N2O17 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-amido-PEG12-acid


Mal-amido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-amido-PEG12-acid

 Mal-amido-PEG12-acid Biological Activity

Description Mal-amido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C34H60N2O17
Molecular Weight 768.84