1334177-79-5
1334177-79-5 structure
- Name: Mal-amido-PEG6-acid
- Chemical Name: 25-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosan-1-oic acid
- CAS Number: 1334177-79-5
- Molecular Formula: C22H36N2O11
- Molecular Weight: 504.528
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-27 10:17:40
- Modify Date: 2024-01-09 08:07:07
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Mal-amido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 25-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosan-1-oic acid |
|---|---|
| Synonyms |
4,7,10,13,16,19-Hexaoxa-22-azapentacosan-1-oic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-
25-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosan-1-oic acid |
| Description | Mal-amido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 702.5±60.0 °C at 760 mmHg |
| Molecular Formula | C22H36N2O11 |
| Molecular Weight | 504.528 |
| Flash Point | 378.7±32.9 °C |
| Exact Mass | 504.231903 |
| LogP | -2.97 |
| Vapour Pressure | 0.0±4.8 mmHg at 25°C |
| Index of Refraction | 1.507 |
| Storage condition | 2-8°C |