1263045-16-4
1263045-16-4 structure
- Name: Mal-amido-PEG4-acid
- Chemical Name: NHS-PEG4-Maleimide
- CAS Number: 1263045-16-4
- Molecular Formula: C18H28N2O9
- Molecular Weight: 416.42300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-12-26 16:57:46
- Modify Date: 2025-08-27 02:38:35
-
Mal-amido-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | NHS-PEG4-Maleimide |
|---|---|
| Synonyms |
19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid
Mal-Amido-PEG4-acid MAL-PEG4-CH2CH2COOH |
| Description | Mal-amido-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C18H28N2O9 |
|---|---|
| Molecular Weight | 416.42300 |
| Exact Mass | 416.17900 |
| PSA | 140.70000 |
| Storage condition | 2-8°C |