299430-87-8
299430-87-8 structure
- Name: Fmoc-N-amido-PEG2-alcohol
- Chemical Name: 9H-fluoren-9-ylmethyl N-[2-(2-hydroxyethoxy)ethyl]carbamate
- CAS Number: 299430-87-8
- Molecular Formula: C19H21NO4
- Molecular Weight: 327.37400
- Catalog: Biochemical Amino acids and their derivatives Amino alcohol derivative
- Create Date: 2018-12-08 17:19:18
- Modify Date: 2024-01-04 09:39:32
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Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 9H-fluoren-9-ylmethyl N-[2-(2-hydroxyethoxy)ethyl]carbamate |
|---|---|
| Synonyms | AmbotzFAL3010 |
| Description | Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.221g/cm3 |
|---|---|
| Boiling Point | 547.8ºC at 760 mmHg |
| Molecular Formula | C19H21NO4 |
| Molecular Weight | 327.37400 |
| Flash Point | 285.1ºC |
| Exact Mass | 327.14700 |
| PSA | 67.79000 |
| LogP | 2.92490 |
| Vapour Pressure | 7.81E-13mmHg at 25°C |
| Index of Refraction | 1.588 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
|
~96%
299430-87-8 |
| Literature: Nasopoulou, Magdalini; Georgiadis, Dimitris; Matziari, Magdalini; Dive, Vincent; Yiotakis, Athanasios Journal of Organic Chemistry, 2007 , vol. 72, # 19 p. 7222 - 7228 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |