Fmoc-N-methyl-PEG3-CH2CH2COOH

Modify Date: 2024-01-05 18:35:09

Fmoc-N-methyl-PEG3-CH2CH2COOH Structure
Fmoc-N-methyl-PEG3-CH2CH2COOH structure
Common Name Fmoc-N-methyl-PEG3-CH2CH2COOH
CAS Number 1807518-77-9 Molecular Weight 413.464
Density 1.2±0.1 g/cm3 Boiling Point 597.4±45.0 °C at 760 mmHg
Molecular Formula C25H31NO7 Melting Point N/A
MSDS N/A Flash Point 315.1±28.7 °C

 Use of Fmoc-N-methyl-PEG3-CH2CH2COOH


Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Fmoc-N-methyl-N-amido-PEG2-acid
Synonym More Synonyms

 Fmoc-N-methyl-PEG3-CH2CH2COOH Biological Activity

Description Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Yang Y,et al. Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4. Bioorg Med Chem. 2016 Nov 1;24(21):5393-5399.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 597.4±45.0 °C at 760 mmHg
Molecular Formula C25H31NO7
Molecular Weight 413.464
Flash Point 315.1±28.7 °C
Exact Mass 413.183838
LogP 3.51
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.573

 Safety Information

Hazard Codes Xi

 Synonyms

2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-4-methyl-3-oxo-
1-(9H-Fluoren-9-yl)-4-methyl-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid
MFCD29918264