Fmoc-NH-PEG10-acid

Modify Date: 2024-01-16 17:22:18

Fmoc-NH-PEG10-acid Structure
Fmoc-NH-PEG10-acid structure
Common Name Fmoc-NH-PEG10-acid
CAS Number 2101563-45-3 Molecular Weight 751.857
Density 1.2±0.1 g/cm3 Boiling Point 826.4±65.0 °C at 760 mmHg
Molecular Formula C38H57NO14 Melting Point N/A
MSDS N/A Flash Point 453.6±34.3 °C

 Use of Fmoc-NH-PEG10-acid


Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-N-amido-PEG10-acid
Synonym More Synonyms

 Fmoc-NH-PEG10-acid Biological Activity

Description Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 826.4±65.0 °C at 760 mmHg
Molecular Formula C38H57NO14
Molecular Weight 751.857
Flash Point 453.6±34.3 °C
Exact Mass 751.377930
LogP 0.15
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.522

 Safety Information

Hazard Codes Xi

 Synonyms

Fmoc-NH-PEG10-CH2CH2COOH
MFCD28122954
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34-undecaoxa-4-azaheptatriacontan-37-oic acid
2,7,10,13,16,19,22,25,28,31,34-Undecaoxa-4-azaheptatriacontan-37-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-