Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Fmoc-NH-PEG3-amide-CH2OCH2COOH
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Fmoc-NH-PEG3-amide-CH2OCH2COOH
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

489427-26-1

489427-26-1 structure

489427-26-1 structure

Name: Fmoc-NH-PEG3-amide-CH2OCH2COOH
Chemical Name: 17-(Fmoc-amino)-5-oxo-6-aza-3,9,12,15-tetraoxaheptadecanoic Acid
CAS Number: 489427-26-1
Molecular Formula: C₂₇H₃₄N₂O₉
Molecular Weight: 530.56700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-11-06 10:29:05
Modify Date: 2025-09-24 17:05:05
Fmoc-NH-PEG3-amide-CH2OCH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	17-(Fmoc-amino)-5-oxo-6-aza-3,9,12,15-tetraoxaheptadecanoic Acid
Synonyms	2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetic acid

Description	Fmoc-NH-PEG3-amide-CH2OCH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.256g/cm3
Boiling Point	794.8ºC at 760 mmHg
Molecular Formula	C₂₇H₃₄N₂O₉
Molecular Weight	530.56700
Flash Point	434.5ºC
Exact Mass	530.22600
PSA	141.65000
LogP	2.57410
Index of Refraction	1.558
Storage condition	2-8°C

489427-25-0 structure

489427-25-0

28920-43-6 structure

28920-43-6

~84%

489427-26-1 structure

489427-26-1

Literature: AMERSHAM HEALTH AS Patent: WO2006/4429 A2, 2006 ; Location in patent: Page/Page column 14 ;

929-75-9 structure

929-75-9

~%

489427-26-1 structure

489427-26-1

Literature: Lindner, Simon; Michler, Christina; Leidner, Stephanie; Rensch, Christian; Waengler, Carmen; Schirrmacher, Ralf; Bartenstein, Peter; Waengler, Bjoern Bioconjugate Chemistry, 2014 , vol. 25, # 4 p. 738 - 749

489427-25-0 structure

489427-25-0

82911-69-1 structure

82911-69-1

~%

489427-26-1 structure

489427-26-1

Literature: Lindner, Simon; Michler, Christina; Leidner, Stephanie; Rensch, Christian; Waengler, Carmen; Schirrmacher, Ralf; Bartenstein, Peter; Waengler, Bjoern Bioconjugate Chemistry, 2014 , vol. 25, # 4 p. 738 - 749

Precursor 3
28920-43-6 929-75-9 82911-69-1
DownStream 0

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.