Fmoc-NH-PEG3-amide-CH2OCH2COOH

Modify Date: 2024-01-08 12:43:13

Fmoc-NH-PEG3-amide-CH2OCH2COOH structure	Common Name	Fmoc-NH-PEG3-amide-CH2OCH2COOH
	CAS Number	489427-26-1	Molecular Weight	530.56700
	Density	1.256g/cm3	Boiling Point	794.8ºC at 760 mmHg
	Molecular Formula	C₂₇H₃₄N₂O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	434.5ºC

Use of Fmoc-NH-PEG3-amide-CH2OCH2COOH

Fmoc-NH-PEG3-amide-CH2OCH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	17-(Fmoc-amino)-5-oxo-6-aza-3,9,12,15-tetraoxaheptadecanoic Acid
Synonym	More Synonyms

Description	Fmoc-NH-PEG3-amide-CH2OCH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

N/A

CAS#:489427-25-0

9-Fluorenylmeth...

CAS#:28920-43-6

~84%

Fmoc-NH-PEG3-am...

CAS#:489427-26-1

Literature: AMERSHAM HEALTH AS Patent: WO2006/4429 A2, 2006 ; Location in patent: Page/Page column 14 ;

Amino-PEG3-C2-Amine

CAS#:929-75-9

Fmoc-NH-PEG3-am...

CAS#:489427-26-1

N/A

CAS#:489427-25-0

Fmoc-Osu

CAS#:82911-69-1

Fmoc-NH-PEG3-am...

CAS#:489427-26-1

Precursor 3
CAS#:28920-43-6 9-Fluorenylmeth... CAS#:929-75-9 Amino-PEG3-C2-Amine CAS#:82911-69-1 Fmoc-Osu
DownStream 0

2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetic acid