867062-95-1
867062-95-1 structure
- Name: Fmoc-NH-PEG3-CH2CH2COOH
- Chemical Name: 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
- CAS Number: 867062-95-1
- Molecular Formula: C24H29NO7
- Molecular Weight: 443.490
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-12-22 19:27:28
- Modify Date: 2024-01-02 12:20:55
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Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid |
|---|---|
| Synonyms |
2,7,10,13-Tetraoxa-4-azahexadecan-16-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
2-[2-[2-(2-aminoethoxy)ethoxy]ethoxymethyl]-3-(9H-fluoren-9-ylmethoxy)-3-oxopropanoic acid 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid Fmoc-12-Amino-4,7,10-Trioxadodecanoic Acid |
| Description | Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Kyoji TSUCHIKAMA, et al. Linkers for antibody drug conjugates. WO2018218004A1. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 651.9±55.0 °C at 760 mmHg |
| Molecular Formula | C24H29NO7 |
| Molecular Weight | 443.490 |
| Flash Point | 348.0±31.5 °C |
| Exact Mass | 443.194397 |
| PSA | 103.32000 |
| LogP | 2.66 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.562 |
| Storage condition | 2-8°C |
| HS Code | 2934999090 |
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| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |