Bis-Tos-PEG7
Modify Date: 2024-01-09 15:56:31
Bis-Tos-PEG7 structure
|
Common Name | Bis-Tos-PEG7 | ||
|---|---|---|---|---|
| CAS Number | 69502-27-8 | Molecular Weight | 634.75600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H42O12S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Bis-Tos-PEG7Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate |
|---|---|
| Synonym | More Synonyms |
| Description | Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C28H42O12S2 |
|---|---|
| Molecular Weight | 634.75600 |
| Exact Mass | 634.21200 |
| PSA | 158.88000 |
| LogP | 4.67540 |
| Hazard Codes | Xn |
|---|
|
~99%
Bis-Tos-PEG7 CAS#:69502-27-8 |
| Literature: Sekiguchi, Hironori; Muranaka, Kazuhiro; Osada, Akiko; Ichikawa, Satoshi; Matsuda, Akira Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 15 p. 5732 - 5737 |
|
~96%
Bis-Tos-PEG7 CAS#:69502-27-8 |
| Literature: Mao, Hua; Thorne, John B.; Pharr, Jennifer S.; Gawley, Robert E. Canadian Journal of Chemistry, 2006 , vol. 84, # 10 p. 1273 - 1279 |
|
~%
Bis-Tos-PEG7 CAS#:69502-27-8 |
| Literature: Chen, Yiyan; Baker, Gregory L. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873 |
|
~%
Bis-Tos-PEG7 CAS#:69502-27-8 |
| Literature: Chen, Yiyan; Baker, Gregory L. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873 |
|
~%
Bis-Tos-PEG7 CAS#:69502-27-8 |
| Literature: Chen, Yiyan; Baker, Gregory L. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873 |
| heptaethylene glycol ditosylate |
| 2-[2-(2-{2-[2-(2-{2-[(4-methylphenyl)sulfonyloxy]ethoxy}ethoxy)ethoxy]ethoxy}e thoxy)ethoxy]ethyl 4-methylbenzenesulfonate |
| 3,6,9,12,15,18-Hexaoxaicosane-1,20-diyl bis(4-methylbenzenesulfonate) |
| 1,20-bis(tosyloxy)-3,6,9,12,15,18-hexaoxaeicosane |
| Heptaethylene glycol di(p-toluenesulfonate) |
| 3,6,9,12,15,18-hexaoxaeicosane-1,20-diol ditosylate |