69502-27-8
69502-27-8 structure
- Name: Bis-Tos-PEG7
- Chemical Name: 2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
- CAS Number: 69502-27-8
- Molecular Formula: C28H42O12S2
- Molecular Weight: 634.75600
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-11-14 13:01:22
- Modify Date: 2024-01-09 15:56:31
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Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate |
|---|---|
| Synonyms |
heptaethylene glycol ditosylate
2-[2-(2-{2-[2-(2-{2-[(4-methylphenyl)sulfonyloxy]ethoxy}ethoxy)ethoxy]ethoxy}e thoxy)ethoxy]ethyl 4-methylbenzenesulfonate 3,6,9,12,15,18-Hexaoxaicosane-1,20-diyl bis(4-methylbenzenesulfonate) 1,20-bis(tosyloxy)-3,6,9,12,15,18-hexaoxaeicosane Heptaethylene glycol di(p-toluenesulfonate) 3,6,9,12,15,18-hexaoxaeicosane-1,20-diol ditosylate |
| Description | Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C28H42O12S2 |
|---|---|
| Molecular Weight | 634.75600 |
| Exact Mass | 634.21200 |
| PSA | 158.88000 |
| LogP | 4.67540 |
| Hazard Codes | Xn |
|---|
| Precursor 6 | |
|---|---|
| DownStream 0 | |