Bis-Tos-(2-hydroxyethyl disulfide)

Modify Date: 2024-01-10 00:17:29

Bis-Tos-(2-hydroxyethyl disulfide) Structure
Bis-Tos-(2-hydroxyethyl disulfide) structure
Common Name Bis-Tos-(2-hydroxyethyl disulfide)
CAS Number 69981-39-1 Molecular Weight 462.62400
Density N/A Boiling Point N/A
Molecular Formula C18H22O6S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-Tos-(2-hydroxyethyl disulfide)


Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name bis(toluolsulfonate)-(2-hydroxyethyl)-disulfide

 Bis-Tos-(2-hydroxyethyl disulfide) Biological Activity

Description Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C18H22O6S4
Molecular Weight 462.62400
Exact Mass 462.03000
PSA 154.10000
LogP 5.95720
Storage condition 2-8°C