N-(Mal-PEG6)-N-bis(PEG7-TCO)

Modify Date: 2025-09-13 08:04:37

N-(Mal-PEG6)-N-bis(PEG7-TCO) structure	Common Name	N-(Mal-PEG6)-N-bis(PEG7-TCO)
	CAS Number	2093152-84-0	Molecular Weight	1652.95
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₈H₁₃₇N₇O₃₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-(Mal-PEG6)-N-bis(PEG7-TCO)

N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Mal-PEG6)-N-bis(PEG7-TCO)

Description	N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₇₈H₁₃₇N₇O₃₀
Molecular Weight	1652.95
InChIKey	LXEACWVJIHRBDM-LEWNYYKSSA-N
SMILES	O=C(CCOCCOCCOCCOCCNC(=O)OC1CCC=CCCC1)NCCOCCOCCOCCN(CCOCCOCCOCCNC(=O)CCOCCOCCOCCOCCNC(=O)OC1CCC=CCCC1)C(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

Hazard Codes	Xi

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