N-Mal-N-bis(PEG4-acid)

Modify Date: 2025-09-12 18:00:12

N-Mal-N-bis(PEG4-acid) structure	Common Name	N-Mal-N-bis(PEG4-acid)
	CAS Number	2100306-52-1	Molecular Weight	664.70
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₄₈N₂O₁₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-Mal-N-bis(PEG4-acid)

Mal-N-bis(PEG4-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-N-bis(PEG4-C2-acid)
Synonym	More Synonyms

Description	Mal-N-bis(PEG4-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₉H₄₈N₂O₁₅
Molecular Weight	664.70

MFCD29912655

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