1964503-35-2

1964503-35-2 structure

1964503-35-2 structure

Name: N-Biotin-N-bis(PEG4-acid)
Chemical Name: N-Biotin-N-bis(PEG4-acid)
CAS Number: 1964503-35-2
Molecular Formula: C₃₂H₅₇N₃O₁₄S
Molecular Weight: 739.87
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 16:12:07
Modify Date: 2024-01-10 10:47:18
N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-Biotin-N-bis(PEG4-acid)
Synonyms	MFCD30458057

Description	N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₂H₅₇N₃O₁₄S
Molecular Weight	739.87