1028089-05-5

1028089-05-5 structure

Name: Tos-PEG7-OH
Chemical Name: PEG8-Tos
CAS Number: 1028089-05-5
Molecular Formula: C₂₁H₃₆O₁₀S
Molecular Weight: 480.569
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-11 08:27:37
Modify Date: 2025-08-26 13:29:17
Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	PEG8-Tos
Synonyms	MFCD24539472 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, benzenesulfonate 2,5,8,11,14,17,20-Heptaoxadocosan-22-yl benzenesulfonate

Description	Tos-PEG7-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.