Amino-PEG4-Boc
Amino-PEG4-Boc structure
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Common Name | Amino-PEG4-Boc | ||
|---|---|---|---|---|
| CAS Number | 581065-95-4 | Molecular Weight | 321.41000 | |
| Density | 1.040±0.06 g/cm3 | Boiling Point | 400.1±35.0 ºC (760 Torr) | |
| Molecular Formula | C15H31NO6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 114.1±22.3 ºC | |
Use of Amino-PEG4-BocAmino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | tert-butyl 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoate |
|---|---|
| Synonym | More Synonyms |
| Description | Amino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.040±0.06 g/cm3 |
|---|---|
| Boiling Point | 400.1±35.0 ºC (760 Torr) |
| Molecular Formula | C15H31NO6 |
| Molecular Weight | 321.41000 |
| Flash Point | 114.1±22.3 ºC |
| Exact Mass | 321.21500 |
| PSA | 89.24000 |
| LogP | 1.44360 |
| Water Solubility | Freely soluble (140 g/L) (25 ºC) |
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Amino-PEG4-Boc CAS#:581065-95-4 |
| Literature: AMBRX, INC.; MIAO, Zhenwei; ATKINSON, Kyle, C.; BIROC, Sandra; BUSS, Timothy; COOK, Melissa; KRAYNOV, Vadim; MARSDEN, Robin; PINKSTAFF, Jason; SKIDMORE, Lillian; SUN, Ying; SZYDLIK, Angieszka; VALENTA, Ianina Patent: WO2012/166560 A1, 2012 ; WO 2012/166560 A1 |
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Amino-PEG4-Boc CAS#:581065-95-4 |
| Literature: AMBRX, INC.; MIAO, Zhenwei; ATKINSON, Kyle, C.; BIROC, Sandra; BUSS, Timothy; COOK, Melissa; KRAYNOV, Vadim; MARSDEN, Robin; PINKSTAFF, Jason; SKIDMORE, Lillian; SUN, Ying; SZYDLIK, Angieszka; VALENTA, Ianina Patent: WO2012/166560 A1, 2012 ; WO 2012/166560 A1 |
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Amino-PEG4-Boc CAS#:581065-95-4 |
| Literature: AMBRX, INC.; MIAO, Zhenwei; ATKINSON, Kyle, C.; BIROC, Sandra; BUSS, Timothy; COOK, Melissa; KRAYNOV, Vadim; MARSDEN, Robin; PINKSTAFF, Jason; SKIDMORE, Lillian; SUN, Ying; SZYDLIK, Angieszka; VALENTA, Ianina Patent: WO2012/166560 A1, 2012 ; WO 2012/166560 A1 |
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Amino-PEG4-Boc CAS#:581065-95-4 |
| Literature: AMBRX, INC.; MIAO, Zhenwei; ATKINSON, Kyle, C.; BIROC, Sandra; BUSS, Timothy; COOK, Melissa; KRAYNOV, Vadim; MARSDEN, Robin; PINKSTAFF, Jason; SKIDMORE, Lillian; SUN, Ying; SZYDLIK, Angieszka; VALENTA, Ianina Patent: WO2012/166560 A1, 2012 ; WO 2012/166560 A1 |
| 15-AMINO-4,7,10,13-TETRAOXA-PENTADECANOIC ACID T-BUTYL ESTER |
| 1-AMINO-3,6,9,12-BUTAOXAPENTADECAN-15-OIC ACID t-Butyl ester |
| tert-butyl 15-amino-4,7,10,13-tetraoxapentadecanoate |
| ter-butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate |
| 15-Amino-4,7,10,13-tetraoxa-pentadecanoic-acid-tert-butylester |
| Amino-PEG4-t-butyl ester |
| AmbotzPEG1375 |
| 2-[2-[2-[2-(2-tert-Butoxycarbonylethoxy)ethoxy]ethoxy]ethoxy]ethylamine |
| H2N-PEG4-CH2CH2COOtBu |