144598-03-8
144598-03-8 structure
- Name: Amino-PEG4-(CH2)3CO2H
- Chemical Name: Amino-PEG4-(CH2)3CO2H
- CAS Number: 144598-03-8
- Molecular Formula: C12H25NO6
- Molecular Weight: 279.330
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-15 03:06:25
- Modify Date: 2024-01-16 19:27:59
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Amino-PEG4-(CH2)3CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Amino-PEG4-(CH2)3CO2H |
|---|---|
| Synonyms |
1-Amino-3,6,9,12-tetraoxahexadecan-16-oic acid
3,6,9,12-Tetraoxahexadecan-16-oic acid, 1-amino- MFCD27977500 |
| Description | Amino-PEG4-(CH2)3CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 421.7±40.0 °C at 760 mmHg |
| Molecular Formula | C12H25NO6 |
| Molecular Weight | 279.330 |
| Flash Point | 208.9±27.3 °C |
| Exact Mass | 279.168182 |
| LogP | -1.71 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.469 |
| Hazard Codes | Xi |
|---|