864680-64-8

864680-64-8 structure

Name: Amino-PEG4-C1-Boc
Chemical Name: Amino-PEG4-C1-Boc
CAS Number: 864680-64-8
Molecular Formula: C₁₄H₂₉NO₆
Molecular Weight: 307.38
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:51:35
Modify Date: 2024-02-01 17:15:50
Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Amino-PEG4-C1-Boc

Description	Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.