1351397-21-1

1351397-21-1 structure

1351397-21-1 structure

Name: Amino-PEG4-benzyl ester
Chemical Name: Amino-PEG4-benzyl ester
CAS Number: 1351397-21-1
Molecular Formula: C₁₈H₂₉NO₆
Molecular Weight: 355.43
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-09 16:18:22
Modify Date: 2024-01-12 18:59:01
Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Amino-PEG4-benzyl ester

Description	Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Byung Chul Lee,et al. Synthesis and biological evaluation of RGD peptides with the 99mTc/188Re chelated iminodiacetate core: highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis. RSC Advances, 2013, 3, 782.

Molecular Formula	C₁₈H₂₉NO₆
Molecular Weight	355.43