Amino-PEG4-hydrazide-Boc

Modify Date: 2025-09-11 14:55:50

Amino-PEG4-hydrazide-Boc Structure
Amino-PEG4-hydrazide-Boc structure
Common Name Amino-PEG4-hydrazide-Boc
CAS Number 1263047-17-1 Molecular Weight 379.449
Density 1.1±0.1 g/cm3 Boiling Point N/A
Molecular Formula C16H33N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG4-hydrazide-Boc


Amino-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 18-amino-4-oxo-7,10,13,16-tetraoxa-2,3-diazaoctadecan-1-oate
Synonym More Synonyms

 Amino-PEG4-hydrazide-Boc Biological Activity

Description Amino-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Molecular Formula C16H33N3O7
Molecular Weight 379.449
Exact Mass 379.231842
LogP -1.25
Index of Refraction 1.474

 Synonyms

7,10,13,16-Tetraoxa-2,3-diazaoctadecan-1-oic acid, 18-amino-4-oxo-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 18-amino-4-oxo-7,10,13,16-tetraoxa-2,3-diazaoctadecan-1-oate
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