Hydroxy-PEG4-(CH2)2-Boc

Modify Date: 2024-01-03 10:28:11

Hydroxy-PEG4-(CH2)2-Boc Structure
Hydroxy-PEG4-(CH2)2-Boc structure
Common Name Hydroxy-PEG4-(CH2)2-Boc
CAS Number 518044-32-1 Molecular Weight 322.39500
Density N/A Boiling Point N/A
Molecular Formula C15H30O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG4-(CH2)2-Boc


Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191).

 Names

Name tert-butyl 3-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)propanoate
Synonym More Synonyms

 Hydroxy-PEG4-(CH2)2-Boc Biological Activity

Description Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191).
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.

 Chemical & Physical Properties

Molecular Formula C15H30O7
Molecular Weight 322.39500
Exact Mass 322.19900
PSA 83.45000
LogP 0.77690

 Synonyms

tert-butyl 3-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]propanoate
tert-butyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate
tert-butyl 15-hydroxy-4,7,10,13-tetraoxapentadecanoate
tert-butyl-15-hydroxy-4,7,10,13-tetraoxapentadecanoate
t-butyl 15-hydroxy-4,7,10,13-tetraoxapentadecanoate
15-Hydroxy-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester
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