Hydroxy-PEG4-O-Boc

Modify Date: 2024-01-31 11:53:27

Hydroxy-PEG4-O-Boc Structure
Hydroxy-PEG4-O-Boc structure
Common Name Hydroxy-PEG4-O-Boc
CAS Number 1807530-05-7 Molecular Weight 352.421
Density 1.1±0.1 g/cm3 Boiling Point 432.4±40.0 °C at 760 mmHg
Molecular Formula C16H32O8 Melting Point N/A
MSDS N/A Flash Point 142.6±20.8 °C

 Use of Hydroxy-PEG4-O-Boc


Hydroxy-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Hydroxy-PEG5-t-butyl acetate
Synonym More Synonyms

 Hydroxy-PEG4-O-Boc Biological Activity

Description Hydroxy-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 432.4±40.0 °C at 760 mmHg
Molecular Formula C16H32O8
Molecular Weight 352.421
Flash Point 142.6±20.8 °C
Exact Mass 352.209717
LogP -0.60
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.454

 Synonyms

MFCD27977509
3,6,9,12,15-Pentaoxaheptadecan-1-oic acid, 17-hydroxy-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 17-hydroxy-3,6,9,12,15-pentaoxaheptadecan-1-oate
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