Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate

Modify Date: 2025-08-27 10:54:58

Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate Structure
Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate structure
Common Name Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate
CAS Number 2228857-35-8 Molecular Weight 280.31
Density N/A Boiling Point N/A
Molecular Formula C12H24O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate


Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Hydroxy-PEG4-C2-methyl ester

  Biological Activity

Description Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H24O7
Molecular Weight 280.31
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