Hydroxy-PEG4-acid

Modify Date: 2024-01-07 11:31:48

Hydroxy-PEG4-acid Structure
Hydroxy-PEG4-acid structure
Common Name Hydroxy-PEG4-acid
CAS Number 937188-59-5 Molecular Weight 266.288
Density 1.2±0.1 g/cm3 Boiling Point 420.7±40.0 °C at 760 mmHg
Molecular Formula C11H22O7 Melting Point N/A
MSDS N/A Flash Point 155.5±20.8 °C

 Use of Hydroxy-PEG4-acid


Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid
Synonym More Synonyms

 Hydroxy-PEG4-acid Biological Activity

Description Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Tinya Abrams, et al. Antibody drug conjugates. WO2016203432A1.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 420.7±40.0 °C at 760 mmHg
Molecular Formula C11H22O7
Molecular Weight 266.288
Flash Point 155.5±20.8 °C
Exact Mass 266.136566
LogP -2.07
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.466

 Synonyms

MFCD22574805
1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid
3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy-