90430-59-4

90430-59-4 structure

Name: Hydroxy-PEG4-methylamine
Chemical Name: 2-[2-[2-[2-(methylamino)ethoxy]ethoxy]ethoxy]ethanol
CAS Number: 90430-59-4
Molecular Formula: C₉H₂₁NO₄
Molecular Weight: 207.26700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-03-22 08:44:45
Modify Date: 2025-08-27 17:26:19
Hydroxy-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-[2-(methylamino)ethoxy]ethoxy]ethoxy]ethanol
Synonyms	5,8,11-Trioxa-2-azatridecan-13-ol

Description	Hydroxy-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562