2062663-63-0

2062663-63-0 structure

2062663-63-0 structure

Name: T-Boc-aminooxy-peg4-ch2co2-t-bu
Chemical Name: Boc-Aminooxy-PEG4-CH2-Boc
CAS Number: 2062663-63-0
Molecular Formula: C₁₉H₃₇NO₉
Molecular Weight: 423.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-07 23:41:51
Modify Date: 2023-02-07 20:17:04
Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-Aminooxy-PEG4-CH2-Boc
Synonyms	MFCD30536164

Description	Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula	C₁₉H₃₇NO₉
Molecular Weight	423.50