HIV-1 inhibitor-55

Modify Date: 2025-08-30 07:00:49

HIV-1 inhibitor-55 Structure
HIV-1 inhibitor-55 structure
Common Name HIV-1 inhibitor-55
CAS Number 2771211-73-3 Molecular Weight 548.66
Density N/A Boiling Point N/A
Molecular Formula C28H32N6O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 inhibitor-55


HIV-1 inhibitor-55 (compound 4d) inhibits WT HIV-1 with an EC50 value of 8.6 nM. HIV-1 inhibitor-55 also shows inhibitory potency against single and double HIV-1 mutants. HIV-1 inhibitor-55 can be used for the research of virus infection[1].

 Names

Name HIV-1 inhibitor-55

 HIV-1 inhibitor-55 Biological Activity

Description HIV-1 inhibitor-55 (compound 4d) inhibits WT HIV-1 with an EC50 value of 8.6 nM. HIV-1 inhibitor-55 also shows inhibitory potency against single and double HIV-1 mutants. HIV-1 inhibitor-55 can be used for the research of virus infection[1].
Related Catalog
In Vitro HIV-1 inhibitor-55 对野生型 HIV-1 表现出抑制作用,EC50 值为 8.6 nM[1]。 HIV-1 inhibitor-55 对 HIV-1 突变体 L100I,K103N,Y181C,Y188L,E138K 和 F227L + V106A 表现出较强的抗逆转录酶活性,其 EC50 值分别为 1.1、0.12、0.36、0.75、0.033 和 3.06 μM[1]。 HIV-1 inhibitor-55 抑制野生型 HIV-1 逆转录的活性,IC50 值为 0.11 μM[1]。
References

[1]. Ming W, et al. Hybrids of delavirdine and piperdin-4-yl-aminopyrimidines (DPAPYs) as potent HIV-1 NNRTIs: Design, synthesis and biological activities. Eur J Med Chem. 2023 Feb 15;248:115114.  

 Chemical & Physical Properties

Molecular Formula C28H32N6O4S
Molecular Weight 548.66
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.