HIV-1 inhibitor-29

Modify Date: 2024-01-08 13:12:06

HIV-1 inhibitor-29 structure	Common Name	HIV-1 inhibitor-29
	CAS Number	2642217-95-4	Molecular Weight	560.64
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₆N₆O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HIV-1 inhibitor-29

HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 μM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 μM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 μM). HIV-1 inhibitor-29 can be used for researching AIDS[1].

Name	HIV-1 inhibitor-29

Description	HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 μM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 μM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 μM). HIV-1 inhibitor-29 can be used for researching AIDS[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	HIV (IIIB):2.18 μM (EC50) HIV-1 (F227L/V106A):0.974 μM (EC50)
References	[1]. Wang Z, Kang D, Feng D, et al. Targeting dual tolerant regions of binding pocket: Discovery of novel morpholine-substituted diarylpyrimidines as potent HIV-1 NNRTIs with significantly improved water solubility. Eur J Med Chem. 2020;206:112811.

Molecular Formula	C₃₀H₃₆N₆O₅
Molecular Weight	560.64

HIV-1 inhibitor-29

Use of HIV-1 inhibitor-29

Names

HIV-1 inhibitor-29 Biological Activity

Chemical & Physical Properties