HIV-1 inhibitor-23

Modify Date: 2024-01-23 16:44:04

HIV-1 inhibitor-23 structure	Common Name	HIV-1 inhibitor-23
	CAS Number	2554622-28-3	Molecular Weight	566.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₆N₆O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HIV-1 inhibitor-23

HIV-1 inhibitor-23 (compound 12a) is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with EC50s of 24.9 nM and 10.4 nM for HIV-1 WT and HIV-1 K103N, respectively. HIV-1 inhibitor-23 has low cytotoxicity (CC50 > 221 μM) and a favorable in vitro microsomal stability[1].

Name	HIV-1 inhibitor-23

Description	HIV-1 inhibitor-23 (compound 12a) is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with EC50s of 24.9 nM and 10.4 nM for HIV-1 WT and HIV-1 K103N, respectively. HIV-1 inhibitor-23 has low cytotoxicity (CC50 > 221 μM) and a favorable in vitro microsomal stability[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1 (WT):24.9 nM (EC50) HIV-1 (K103N):10.4 nM (EC50)
References	[1]. Han S, et al. Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors. Eur J Med Chem. 2020;185:111874.

Molecular Formula	C₃₀H₂₆N₆O₄S
Molecular Weight	566.63

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

HIV-1 inhibitor-23

Use of HIV-1 inhibitor-23

Names

HIV-1 inhibitor-23 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.