HIV-1 inhibitor-42

Modify Date: 2025-09-09 20:57:57

HIV-1 inhibitor-42 Structure
HIV-1 inhibitor-42 structure
Common Name HIV-1 inhibitor-42
CAS Number 2459929-46-3 Molecular Weight 424.47
Density N/A Boiling Point N/A
Molecular Formula C22H20N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 inhibitor-42


HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 μM[1].

 Names

Name HIV-1 inhibitor-42

 HIV-1 inhibitor-42 Biological Activity

Description HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 μM[1].
Related Catalog
Target

HIV-1:0.06 ± 0.0 μM (IC50)

HIV-1 (Y181C):15.510 ± 1 μM (IC50)

HIV-1 (K103N):53.045 ± 6 μM (IC50)

References

[1]. Yi-MingLi, et al. Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. September 2020;102:104041.

 Chemical & Physical Properties

Molecular Formula C22H20N2O5S
Molecular Weight 424.47
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