6-Chloroguanineriboside

Modify Date: 2024-01-03 01:32:16

6-Chloroguanineriboside structure	Common Name	6-Chloroguanineriboside
	CAS Number	2004-07-1	Molecular Weight	301.69
	Density	2.2±0.1 g/cm3	Boiling Point	729.9±70.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₂ClN₅O₄	Melting Point	165-167 °C (dec.)(lit.)
	MSDS	USA	Flash Point	395.2±35.7 °C

Use of 6-Chloroguanineriboside

6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-Amino-6-chloropurine-9-riboside
Synonym	More Synonyms

Description	6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	2.2±0.1 g/cm3
Boiling Point	729.9±70.0 °C at 760 mmHg
Melting Point	165-167 °C (dec.)(lit.)
Molecular Formula	C₁₀H₁₂ClN₅O₄
Molecular Weight	301.69
Flash Point	395.2±35.7 °C
Exact Mass	301.057770
PSA	139.54000
LogP	-0.59
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.912
Storage condition	−20°C

6-Chloroguanineriboside MSDS(Chinese)

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

Precursor 9
CAS#:16321-99-6 2',3',5'-Tri-O-... CAS#:108321-99-9 D-RIBULOSE 5-PH... CAS#:10310-21-1 2-Amino-6-chlor... CAS#:81100-62-1 7-methylguanosi...
CAS#:118-00-3 Guanosine CAS#:6979-94-8 2',3',5'-Triace... CAS#:67-56-1 Methanol CAS#:3387-63-1 2-amino-6-chlor...
CAS#:28708-32-9 tetraacetylribo...
DownStream 10
CAS#:109881-25-6 2,6-diaminopuri... CAS#:107550-73-2 2,6-diaminopuri... CAS#:4546-54-7 2-amino-9-(β-D-... CAS#:5987-76-8 6-Chloro-2-iodo...
CAS#:35109-88-7 2-Iodoadenosine CAS#:29411-74-3 Guanosine, 6-seleno- CAS#:7803-88-5 6-O-Methyl Guanosine CAS#:3616-24-8 9H-Purin-2-amin...
CAS#:313477-85-9 (2S,3R,4S,5R)-2... CAS#:16321-99-6 2',3',5'-Tri-O-...

Preparative electrochemical reduction of 2-amino-6-chloropurine and synthesis of 6-deoxyacyclovir, a fluorescent substrate of xanthine oxidase and a prodrug of acyclovir.

Acta Chem. Scand. B 41 , 701-707, (1987)

D.c. polarography of 2-amino-6-chloropurine in aqueous medium over a broad pH range revealed two diffusion waves, the first of which corresponds to reduction of the C(6)-Cl bond, leading to formation ...

Synthesis of a mutagenic nucleoside, 2'-deoxy-2-(p-nitrophenyl)-adenosine.

Nucleic Acids Symp. Ser. 17 , 141-143, (1986)

The reaction of 2-amino-6-chloropurine riboside with i-amyl nitrite in benzene in the presence of Cu2O, followed by treatment with NH3/MeOH gave 2-phenyladenosine (1). The crude sample of 1 was found ...

Synthesis of 6-arylthio analogs of 2',3'-dideoxy-3'-fluoroguanosine and their effect against hepatitis B virus replication.

Nucleosides Nucleotides Nucleic Acids 25 , 655-665, (2006)

A key compound, 2-amino-6-chlor-9-(2,3-dideoxy-3-fluoro-beta-D-erythro-pentofuranosyl)puine, was prepared from 2-amino-6-chloropurine riboside in 5 steps, then subjected to the nucleophilic displaceme...

(−)-2-Amino-6-chloropurine riboside 6-Chloroguanine riboside

6-Chloroguanineriboside

2-Amino-6-chloro-9-(β-D-ribofuranosyl)purine

6-Chloro-9-(β-D-ribofuranosyl)-9H-purin-2-amine

EINECS 217-905-3

(−)-2-Amino-6-chloropurine riboside

6-CHLOROGUANOSINE

2-Amino-6-chloropurine Riboside

6-Chloroguanine nucleoside

6-CHLOROADENOSINE

6-Chloroguanosine2

MFCD00005735

2-Amino-6-chloropurine-9--D-riboside

9H-Purin-2-amine, 6-chloro-9-β-D-ribofuranosyl-

6-Chloroguanine riboside

2-amino-6-chloro purineriboside

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 6-Chloroguanineriboside
Price: ￥108.0/1g ￥148.0/5g
Purity: 97.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Amino-6-chloropurine-9-riboside
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 2-Amino-6-chloropurine-9-riboside
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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6-Chloroguanineriboside

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