6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
Modify Date: 2024-01-03 19:48:44
6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine structure
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Common Name | 6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine | ||
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| CAS Number | 5987-76-8 | Molecular Weight | 538.68 | |
| Density | 1.98g/cm3 | Boiling Point | 643.3ºC at 760 mmHg | |
| Molecular Formula | C16H16ClIN4O7 | Melting Point | 181-183ºC | |
| MSDS | N/A | Flash Point | 342.9ºC | |
Use of 6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine |
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| Synonym | More Synonyms |
| Description | 6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 1.98g/cm3 |
|---|---|
| Boiling Point | 643.3ºC at 760 mmHg |
| Melting Point | 181-183ºC |
| Molecular Formula | C16H16ClIN4O7 |
| Molecular Weight | 538.68 |
| Flash Point | 342.9ºC |
| Exact Mass | 537.97500 |
| PSA | 131.73000 |
| LogP | 1.40820 |
| Index of Refraction | 1.713 |
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~88%
6-Chloro-2-iodo... CAS#:5987-76-8 |
| Literature: Gruenewald, Christian; Kwon, Taewoo; Piton, Nelly; Foerster, Ute; Wachtveitl, Josef; Engels, Joachim W. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 1 p. 19 - 26 |
|
~85%
6-Chloro-2-iodo... CAS#:5987-76-8 |
| Literature: Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252 |
|
~%
6-Chloro-2-iodo... CAS#:5987-76-8 |
| Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 5-7 p. 717 - 720 |
|
~80%
6-Chloro-2-iodo... CAS#:5987-76-8 |
| Literature: Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252 |
|
~%
6-Chloro-2-iodo... CAS#:5987-76-8 |
| Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 5-7 p. 717 - 720 |
|
~62%
6-Chloro-2-iodo... CAS#:5987-76-8 |
| Literature: Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252 |
|
~%
6-Chloro-2-iodo... CAS#:5987-76-8 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 12, # 11 p. 2995 - 3007 |
| Precursor 6 | |
|---|---|
| DownStream 7 | |
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CAS#:403620-92-8| acetic acid (2r,3r,4r,5r)-3,4-diacetoxy-5-(6-chloro-2-iodo-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester |
| MFCD03701153 |