(2S,3R,4S,5R)-2-((6-CHLORO-2-IODO-9H-PURIN-9-YL)OXY)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL

Modify Date: 2025-09-10 22:36:02

(2S,3R,4S,5R)-2-((6-CHLORO-2-IODO-9H-PURIN-9-YL)OXY)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL structure	Common Name	(2S,3R,4S,5R)-2-((6-CHLORO-2-IODO-9H-PURIN-9-YL)OXY)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL
	CAS Number	313477-85-9	Molecular Weight	412.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₀ClIN₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (2S,3R,4S,5R)-2-((6-CHLORO-2-IODO-9H-PURIN-9-YL)OXY)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL

9H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl- (6-CHLORO-2-IODOPURINE-9-RIBOSIDE) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2S,3R,4S,5R)-2-((6-Chloro-2-iodo-9H-purin-9-yl)-oxy)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Synonym	More Synonyms

Description	9H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl- (6-CHLORO-2-IODOPURINE-9-RIBOSIDE) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₀H₁₀ClIN₄O₄
Molecular Weight	412.57
Exact Mass	427.93800
PSA	122.75000

6-Chloroguanine...

CAS#:2004-07-1

~54%

(2S,3R,4S,5R)-2...

CAS#:313477-85-9

Literature: Bressi; Choe; HoughHough; Buckner; Van Voorhis; Verlinde; Hol; Gelb Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4135 - 4150

Precursor 1
CAS#:2004-07-1 6-Chloroguanine...
DownStream 1
CAS#:35109-88-7 2-Iodoadenosine

6-Chloro-2-iodopurine riboside

6-CHLORO-2-IODOPURINE-9-RIBOSIDE

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(2S,3R,4S,5R)-2-((6-CHLORO-2-IODO-9H-PURIN-9-YL)OXY)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL

Use of (2S,3R,4S,5R)-2-((6-CHLORO-2-IODO-9H-PURIN-9-YL)OXY)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.