313477-85-9
313477-85-9 structure
- Name: (2S,3R,4S,5R)-2-((6-CHLORO-2-IODO-9H-PURIN-9-YL)OXY)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL
- Chemical Name: (2S,3R,4S,5R)-2-((6-Chloro-2-iodo-9H-purin-9-yl)-oxy)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- CAS Number: 313477-85-9
- Molecular Formula: C10H10ClIN4O4
- Molecular Weight: 412.57
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2018-06-21 11:28:49
- Modify Date: 2025-09-10 22:36:02
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9H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl- (6-CHLORO-2-IODOPURINE-9-RIBOSIDE) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | (2S,3R,4S,5R)-2-((6-Chloro-2-iodo-9H-purin-9-yl)-oxy)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
|---|---|
| Synonyms |
6-Chloro-2-iodopurine riboside
6-CHLORO-2-IODOPURINE-9-RIBOSIDE |
| Description | 9H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl- (6-CHLORO-2-IODOPURINE-9-RIBOSIDE) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C10H10ClIN4O4 |
|---|---|
| Molecular Weight | 412.57 |
| Exact Mass | 427.93800 |
| PSA | 122.75000 |
|
~54%
313477-85-9 |
| Literature: Bressi; Choe; HoughHough; Buckner; Van Voorhis; Verlinde; Hol; Gelb Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4135 - 4150 |
| Precursor 1 | |
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| DownStream 1 | |
