2-Amino-6-chloropurine structure
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Common Name | 2-Amino-6-chloropurine | ||
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CAS Number | 10310-21-1 | Molecular Weight | 169.57 | |
Density | 1.8±0.1 g/cm3 | Boiling Point | 315.2ºC at 760mmHg | |
Molecular Formula | C5H4ClN5 | Melting Point | >300 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 144.4ºC |
Use of 2-Amino-6-chloropurine6-Chloroguanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
Name | 6-chloroguanine |
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Synonym | More Synonyms |
Description | 6-Chloroguanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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Related Catalog | |
In Vitro | 2-Amino-6-chloropurine 是合成核苷酸类似物的前体,具有抗 Epstein-Barr 病毒 (EBV) 和人类疱疹病毒 6 (HHV-6) 的抗病毒活性。11.Qiu, Y.-L., Ksebati, MB, Ptak, RG, et al.(Z)-和 (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine 和-guanine。具有广谱抗病毒活性的新型核苷酸类似物 J.医学。化学 41(1) 10-23 (1998) |
References |
Density | 1.8±0.1 g/cm3 |
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Boiling Point | 315.2ºC at 760mmHg |
Melting Point | >300 °C(lit.) |
Molecular Formula | C5H4ClN5 |
Molecular Weight | 169.57 |
Flash Point | 144.4ºC |
Exact Mass | 169.015518 |
PSA | 80.48000 |
LogP | -0.03 |
Vapour Pressure | 1.75E-15mmHg at 25°C |
Index of Refraction | 1.827 |
Storage condition | Keep Cold |
Water Solubility | 1.7 g/L (20 ºC) |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi,Xn |
Risk Phrases | R20/21/22 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | UO7502000 |
HS Code | 2933990090 |
~68% 2-Amino-6-chlor... CAS#:10310-21-1 |
Literature: Luo, Lei; Chen, Guorong; Li, Yuanchao Heterocycles, 2008 , vol. 75, # 11 p. 2803 - 2808 |
~85% 2-Amino-6-chlor... CAS#:10310-21-1 |
Literature: Hu, Yu Lin; Ge, Qiang; Lu, Ming; Lu, Hong Fei Bulletin of the Chemical Society of Ethiopia, 2010 , vol. 24, # 3 p. 425 - 432 |
~86% 2-Amino-6-chlor... CAS#:10310-21-1 |
Literature: Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N. Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511 |
~% 2-Amino-6-chlor... CAS#:10310-21-1 |
Literature: Journal of Heterocyclic Chemistry, , vol. 48, # 5 p. 1140 - 1144 |
~% 2-Amino-6-chlor... CAS#:10310-21-1 |
Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 30, # 7-8 p. 503 - 511 |
Precursor 5 | |
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DownStream 9 | |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
Bioorg. Med. Chem. 15 , 3450-6, (2007) Xanthine oxidase (XO) is a key enzyme which can catalyze xanthine to uric acid causing hyperuricemia in humans. By using the fractionation technique and inhibitory activity assay, an active compound t... |
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Molecular crowding enhances facilitated diffusion of two human DNA glycosylases.
Nucleic Acids Res. 43 , 4087-97, (2015) Intracellular space is at a premium due to the high concentrations of biomolecules and is expected to have a fundamental effect on how large macromolecules move in the cell. Here, we report that crowd... |
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Additive Pummerer reaction of 3,5-O-(di-tert-butyl)silylene-4-thiofuranoid glycal: a high-yield and beta-selective entry to 4'-thioribonucleosides.
J. Org. Chem. 74(6) , 2616-9, (2009) Upon reacting 3,5-O-(di-tert-butyl)silylene-4-thiofuranoid glycal S-oxide (6) with Ac(2)O/TMSOAc/BF(3) x OEt(2) in CH(2)Cl(2), the additive Pummerer reaction proceeded to furnish the corresponding 1,2... |
2-Amino-6-Chloro-Purin |
2-Amino-6-chloropurine |
MFCD00075252 |
EINECS 233-686-7 |
6-Chloroguanine |
9H-Purin-2-amine, 6-chloro- |
6-Chloro-3H-purin-2-amine |
2-AMINO-6-CHLORO-PURINE |