120595-72-4
120595-72-4 structure
- Name: 2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE
- Chemical Name: (2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
- CAS Number: 120595-72-4
- Molecular Formula: C10H12ClN5O3
- Molecular Weight: 285.69
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2018-12-25 09:13:17
- Modify Date: 2025-09-04 15:39:09
-
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | (2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol |
|---|---|
| Synonyms |
2-AMINO-6-CHLOROPURINE-2`-DEOXYRIBOSIDE
2-amino-6-chloro-2'-deoxyguanosine carbocyclic 2-amino-6-chloro-2'-deoxyadenosine |
| Description | 2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C10H12ClN5O3 |
|---|---|
| Molecular Weight | 285.69 |
| Exact Mass | 285.06300 |
| PSA | 119.31000 |
| LogP | 0.28380 |
|
~94%
120595-72-4 |
| Literature: Noguchi, Toshitada; Hamamoto, Tomoki; Okuyama, Kiyoshi; Shibuya, Susumu Patent: US2005/170470 A1, 2005 ; Location in patent: Page/Page column 7 ; |
|
~65%
120595-72-4 |
| Literature: Hanna; Ramasamy; Robins; Revankar Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1899 - 1903 |
|
~67%
120595-72-4 |
| Literature: Okuyama, Kiyoshi; Shibuya, Susumu; Hamamoto, Tomoki; Noguchi, Toshitada Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 5 p. 989 - 995 |
|
~%
120595-72-4 |
| Literature: Hanna; Ramasamy; Robins; Revankar Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1899 - 1903 |
| Precursor 4 | |
|---|---|
| DownStream 1 | |
