2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE structure
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Common Name | 2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE | ||
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| CAS Number | 120595-72-4 | Molecular Weight | 285.69 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H12ClN5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | (2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol |
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| Synonym | More Synonyms |
| Description | 2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C10H12ClN5O3 |
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| Molecular Weight | 285.69 |
| Exact Mass | 285.06300 |
| PSA | 119.31000 |
| LogP | 0.28380 |
| InChIKey | LEDIVMUMDVEFRG-KVQBGUIXSA-N |
| SMILES | Nc1nc(Cl)c2ncn(C3CC(O)C(CO)O3)c2n1 |
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~94%
2-AMINO-6-CHLOR... CAS#:120595-72-4 |
| Literature: Noguchi, Toshitada; Hamamoto, Tomoki; Okuyama, Kiyoshi; Shibuya, Susumu Patent: US2005/170470 A1, 2005 ; Location in patent: Page/Page column 7 ; |
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~65%
2-AMINO-6-CHLOR... CAS#:120595-72-4 |
| Literature: Hanna; Ramasamy; Robins; Revankar Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1899 - 1903 |
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~67%
2-AMINO-6-CHLOR... CAS#:120595-72-4 |
| Literature: Okuyama, Kiyoshi; Shibuya, Susumu; Hamamoto, Tomoki; Noguchi, Toshitada Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 5 p. 989 - 995 |
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~%
2-AMINO-6-CHLOR... CAS#:120595-72-4 |
| Literature: Hanna; Ramasamy; Robins; Revankar Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1899 - 1903 |
| 2-AMINO-6-CHLOROPURINE-2`-DEOXYRIBOSIDE |
| 2-amino-6-chloro-2'-deoxyguanosine |
| carbocyclic 2-amino-6-chloro-2'-deoxyadenosine |